Azkona, G., Caballero, J. M. 2019. Implementing strategies to reduce singly housed male mice. Laboratory Animals 53(5), 508–510.
There are different husbandry situations that lead to social isolation of male mice. Besides legal considerations, single housing has a negative impact on behavioural and molecular studies. We have implemented two strategies, the ‘companion mouse’ and just-weaned male grouping, to reduce the number of male mice housed singly in our facility. We have achieved a progressive reduction (42% in three years) without an increase in aggression.