Laboratory

Wharton, K. N., Walsh, C. A., Haulter, M. et al. 2024. Sedation efficacy of midazolam in conjunction with ketamine and alfaxalone in female laboratory guinea pigs (Cavia porcellus). JAALAS 63(5), 572–580.

Guinea pigs have been integral as models used in biomedical research, making significant contributions to nutritional, auditory, immunologic, and hypersensitivity studies, and necessitating the routine need for sedation in laboratory settings. The ketamine-xylazine (KX) combination...

Weisbroth, S. H. 2024. The use of rabbits used to propagate human lice for research. Comparative Medicine 74(3), 135–141.

The globally important human diseases of trench fever, epidemic typhus, and relapsing fever are vectored by the human louse Pediculus humanus humanus. Although these conditions are epidemically quiescent at present, they persist in socially dysfunctional...

Vanhecke, D., Bugada, V., Steiner, R. et al. 2024. Refined tamoxifen administration in mice by encouraging voluntary consumption of palatable formulations. Lab Animal 53(8), 205–214.

Drug administration in preclinical rodent models is essential for research and the development of novel therapies. Compassionate administration methods have been developed, but these are mostly incompatible with water-insoluble drugs such as tamoxifen or do...