Laboratory

Hampton, J. O., Hemsworth, L. M., Hemsworth, P. H. et al. 2023. Rethinking the utility of the Five Domains model. Animal Welfare 32, e62.

The Five Domains model is influential in contemporary studies of animal welfare. It was originally presented as a conceptual model to understand the types of impact that procedures may impose on experimental animals. Its application...

Gutmann, S., Heiderhoff, M., Möbius, R. et al. 2023. Application accuracy of a frameless optical neuronavigation system as a guide for craniotomies in dogs. Acta Veterinaria Scandinavica 65(1), 54.

Optical neuronavigation systems using infrared light to create a virtual reality image of the brain allow the surgeon to track instruments in real time. Due to the high vulnerability of the brain, neurosurgical interventions must...

Goodwin, N., Keeble, R., Price, M. 2023. The zebrafish health and welfare database, where we are now. Animal Technology and Welfare 22(3), 231–232.

In 2019 the first Zebrafish health and welfare terms database was created. Working in collaboration with Zebrafish specialists and veterinarians we defined severity scores, welfare indicators, definitions and images to form a resource for the...

Ciupa, J. 2023. The hard-hitting tooth—Does a scheduled teeth check reduce the number of mice found dead with malocclusion? Animal Technology and Welfare 22(3), 240–241.

Malocclusion is evident around the first 2-5 weeks of age for mice (NC3Rs, 2021). Therefore, it is hypothesised that a regular welfare check, the POST WEAN CHECK (PWC) at 5 weeks would: - significantly increase...

Burciaga, L. M., Alcaraz, G. 2023. Metabolic and behavioural effects of hermit crab shell removal techniques: Is heating less invasive than cracking? Animal Welfare 32, e24.

Hermit crabs (Paguroidea; Latreille 1802) offer great opportunities to study animal behaviour and physiology. However, the animals’ size and sex cannot be determined when they are inside their shell; information crucial to many experimental designs...

Beechener, S., Brown, S., Bombail, V. et al. 2023. An exploratory interview study of researchers’ and technicians’ perceptions of rat tickling. Animal Technology and Welfare 22(3), 201–209.

This paper highlights the main themes which emerged from a study carried out with Animal Technicians and researchers to better understand: - perceptions of rat tickling - potential drivers and barriers to the uptake of...

Stærk, K., Langhorn, L., Andersen, T. E. 2023. Clean-catching urine from pigs: A method for collecting quality specimens for urinalysis and microbiological culturing in a laboratory environment. Laboratory Animals 57(3), 293–303.

Urine is an important biological specimen for assessing various metabolic functions and drug clearance. In urinary tract infection research, urine is particularly important as urinary bacterial titres constitute the main diagnostic outcome for assessing the...

Spalinger, M., Schwarzfischer, M., Niechcial, A. et al. 2023. Evaluation of the effect of tramadol, paracetamol and metamizole on the severity of experimental colitis. Laboratory Animals 57(5), 529–540.

Application of dextran sodium sulfate (DSS) is often used to induce experimental colitis. Current state of the art is to refrain from the use of analgesics due to their possible interaction with the model. However...

Schelde, K., Rosenjack, J., Sonneborn, C. et al. 2023. A minimally invasive bronchoscopic approach for direct delivery to murine airways and application to models of pulmonary infection. Laboratory Animals 57(6), 611–622.

The laboratory mouse is used extensively for human disease modeling and preclinical therapeutic testing for efficacy, biodistribution, and toxicity. The variety of murine models available, and the ability to create new ones, eclipses all other...

Ringer, S. K., Schmid, A., Weiss, M. et al. 2023. Non-surgical external jugular vein catheterization using an ear vein access in piglets. Laboratory Animals 57(6), 642–649.

The objective of this study was to investigate the feasibility of external jugular vein catheterization through an ear vein in piglets. Forty-six sevoflurane-midazolam anaesthetized piglets were included. External jugular vein catheterization was conducted through the...

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