The question was asked: "In your own experience, what is the least disturbing technique - from the subject's point of view! - of blood collection for rodents?" In summary, it is fair to conclude the...
A review of the literature shows that a consensus on the definition of changes constituting environmental enrichment has yet to be reached. For this reason, the results of studies on the effects of rodent enrichment...
Some recommendations in the Guide for the Care and Use of Laboratory Animals (the Guide) are based on best professional judgment. Our current efforts are directed toward replacement with data-driven standards. We demonstrated earlier that...
This article provides details to consider when preparing to use animals in biomedical research. The stress of transport and receipt of animals into a new environment mandate the need for a period of stabilization and...
The aim of the study was to investigate effects of widely recommended nesting material and additional shelters on male mice. The aggressiveness of the mice in their home cages clearly increased in the nest group,as...
It was found that heart rate (HR), and to a lesser extent also body temperature (BT), parallels plasma corticosterone (pCORT) values after subjecting the animals to different methods of restraint. Secondly, the acute stress response...
Our experience-based discussion suggests that social animals benefit from compatible companionship during post-operative recovery. The traditional practice of keeping animals alone in an unfamiliar environment after surgery increases the subjects surgery-associated stress. Providing a familiar...
I conclude from our discussion that commercial prefabricated dwellings for mice are useful only if they are made of GLP-accepted material that the animals can readily gnaw and convert into nesting and bedding material. Since...
In this article, recent publications are examined to determine the potential impact of new scientific evidence on current practices for the housing and care of laboratory rodents. The discussion points out recent advances in technology...
Objective: To investigate the positive effects of four different forms of environmental enrichment on the welfare of mice subjected to restraint stress with the purpose of screening suitable enrichment. Method: Mice undergoing poor welfare due...