Mouse

Paronis, E., Kapogiannatou, A., Paschidis, K. et al. 2018. Lighting environment: What colour of light do male C57BL/6J prefer? Applied Animal Behaviour Science 209, 99-103.

Environmental factors applied in animal research facilities need to be regulated accurately not only for the welfare of laboratory animals but also for the reliability of the experimental results. However, the effect of lighting environment...

Trindade Madeira Araújo, F., de Cássia Espírito Santo, L., Peixoto Teixeira, A. C. et al. 2018. Low welfare impact of noise: Assessment in an experimental model of mice infected by Herpes simplex-1. Applied Animal Behaviour Science 207, 79-88.

The breeding practices adopted and the equipment typically found in animal facilities produce sounds at frequencies within the auditory range of the mice (1 to 100 kHz), which can cause hearing and other non-hearing effects...

Blankenberger, W. B., Weber, E. M., Chu, D. K. et al. 2018. Breaking up is hard to do: Does splitting cages of mice reduce aggression? Applied Animal Behaviour Science 206, 94-101.

Injurious aggression in group housed male laboratory mice is a common welfare issue that can also negatively affect study outcomes. Often, one mouse in the cage appears unwounded, and the current standard practice is to...

Fiebig, K., Jourdan, T., Kock, M. H. et al. 2018. Evaluation of infrared thermography for temperature measurement in adult male NMRI nude mice. JAALAS 57(6), 715–724.

Temperature monitoring during critical care provides important data required to guide treatment delivery. Body temperature is an easily quantified clinical parameter that can yield much information concerning the health of an animal. In research settings...

Garner, A. M., Norton, J. N., Kinard, W. L., et al. 2018. Vibration-induced behavioral responses and response threshold in female C57BL/6 mice. JAALAS 57(5), 447–455.

Despite documented adverse effects, limits for rodent exposure to vibration in the laboratory animal facility have not been established. This study used female C57BL/6 mice to determine the frequencies of vibration at which mice were...

Creamer-Hente, M. A., Lao, F. K., Dragos, Z. P. et al. 2018. Sex- and strain-related differences in the stress response of mice to CO₂ euthanasia. JAALAS 57(5), 513–519.

The 2013 edition of the AVMA Guidelines for the Euthanasia of Animals recommends a 10% to 30% volume displacement rate (VDR) per minute for CO2 euthanasia of rodents. Here we sought to evaluate behavior and...

Cho, C., Michalidis, V., Lecker, I. et al. 2019. Evaluating analgesic efficacy and administration route following craniotomy in mice using the grimace scale. Scientific Reports 9, 359.

Most research laboratories abide by guidelines and mandates set by their research institution regarding the administration of analgesics to control pain during the postoperative period. Unfortunately, measuring pain originating from the head is difficult, making...

Fehlhaber, B., Heinemann, A. S., Rübensam, K. et al. 2019. A sensitive scoring system for the longitudinal clinical evaluation and prediction of lethal disease outcomes in newborn mice. Scientific Reports 9, 5919.

Neonatal animal models are increasingly employed in order to unravel age-specific disease mechanisms. Appropriate tools objectifying the clinical condition of murine neonates are lacking. In this study, we tested a scoring system specifically designed for...

Makowska, I. J., Franks, B., El-Hinn, C. et al. 2019. Standard laboratory housing for mice restricts their ability to segregate space into clean and dirty areas. Scientific Reports 9, 6179.

Laboratory mice (Mus musculus) are typically housed in simple cages consisting of one open space. These standard cages may thwart mouse ability to segregate resting areas from areas where they eliminate, a behaviour that is...

Lidster, K., Jefferys, J. G., Blümcke, I. et al. 2016. Opportunities for improving animal welfare in rodent models of ep

Animal models of epilepsy and seizures, mostly involving mice and rats, are used to understand the pathophysiology of the different forms of epilepsy and their comorbidities, to identify biomarkers, and to discover new antiepileptic drugs...

Subscribe to Mouse