Advances in facility design, healthcare, and other strategies have produced an excellent quality of life for chimpanzees (Pan troglodytes) in biomedical research. Historically, many facilities housed chimpanzees individually or in small groups (2–3 animals). Laboratory...
It is now more than 20 years since both Council of Europe Convention ETS123 and EU Directive 86/609/EEC were introduced, to promote the implementation of the Three Rs in animal experimentation and to provide guidance...
To do justice to the diverse approaches to enrichment and behavioral management around the world would entail a discussion beyond the limits of this publication. Therefore, guidelines and regulations in a representative sample of countries...
COST Action B-24 established four working groups to research and discuss issues relevant to laboratory animal science. These included the housing of animals, environmental needs, refinement of procedures, genetically modified animals, and cost-benefit analysis. Based...
Most regulations governing animal experimentation require that the harms expected to be incurred by animal subjects should be balanced against the likely benefits of the project. Too often, however, expected human benefits are based on...
Originally enacted in 1966, the Laboratory Animal Welfare Act has been amended several times and renamed the Animal Welfare Act. Responsibility for administering the Animal Welfare Act was delegated within the United States Department of...
Clinical Laboratory Animal Medicine: An Introduction, Fourth Edition offers a user-friendly guide to the unique anatomy and physiology, care, common diseases, and treatment of small mammals and nonhuman primates. Carefully designed for ease of use...
Replacement, Reduction and Refinement, the Three Rs of Russell & Burch, are accepted worldwide as fundamental to the ethics of animal experimentation. The production, care and use of genetically-altered animals can pose particular challenges to...