Stress can influence a number of physiological processes including adult neurogenesis, metabolism, cardiovascular function, immune function, neurophysiological function, endocrine function and inflammatory processes following injury. In testing drugs which may be used to treat various...
A new application of a device enabling the long-term enteral administration of drugs or nutritional supplementation was developed for implementing in research entailing the use of macaques (Macaca fascicularis). After implanting a subcutaneous port, a...
An adequate analgesic strategy is important to improve the postoperative recovery and welfare of laboratory rats and mice. It is desirable that the method for administering the drug is non-invasive and stress-free. We have previously...
Positive reinforcement training (PRT) methods can be applied to gain the voluntary cooperation of laboratory primates with the collection of biological samples. Information will be provided on training techniques used and the amount of training...
The transportation of mice into a new clean cage after surgery is a standard procedure but might have detrimental effects during the critical post-surgical recovery phase. To analyse the effect of post-surgical housing, female C57BL/6J...
The impact of operantly training domestic cats to accept jugular blood collections in a dorsally recumbent (novel) position was assessed. Cats were assigned to one of three groups: Group 1 (N = 14): no training...
Repeated blood sampling from laboratory animals is desirable in certain experimental designs and also for reducing the number of animals used in research. Biochemical methods for analysing blood samples require only small blood volumes to...
There is increased regulatory emphasis on positive reinforcement training for husbandry, research procedures, and restraint devices. We practice acclimation, association, and positive reinforcement training with our beagle colony with goals to reduce stress for dogs...
Conventional bleeding of small laboratory animals is often associated with stress and injuries that can cause haematomas, inflammation and ultimately the death of animals under investigation. Here, we used faecal glucocorticoid metabolites as an indicator...
This is the third volume of discussions that took place on the Laboratory Animal Refinement & Enrichment Forum (LAREF). This forum is dedicated to the exchange of personal experiences of refining the conditions under which...