Endotracheal intubation of laboratory animals is a common procedure shared by several research fields for different purposes, such as mechanical ventilation of anaesthetized animals, instillation of cytotoxic nanoparticles, infectious agents or tumour cells for induction...
Repeated anaesthesia may be required in experimental protocols and in daily veterinary practice, but anaesthesia is known to alter physiological parameters in GPs (Cavia porcellus, GPs). This study investigated the effects of repeated anaesthesia with...
Laboratory animals are still necessary in scientific investigation and vaccine testing, but while novel methodological approaches are not available for their replacement, the search for new, humane, easy, and painless methods is necessary to diminish...
Guinea pigs (GPs) are difficult to anaesthetize successfully, the choices for anaesthesia are limited and physiological parameters are likely to be influenced substantially under anaesthesia. We implanted blood pressure radio-telemetry devices into 16 male GPs...
Evidence for the hypothesis that brain-opioids mediate social affect and social attachments is summarized. Opiates and opioids are very effective in reducing social separation-induced distress vocalizations (DVs), in puppies, young guinea pigs and chicks, while...
Initial attempts to provide the animals a covered area for refuge showed that the guinea pigs adopted the shelter very quickly and would dart under cover when startled. ... We soon realized that this was...
Group housing [female] guinea pigs can save space and money, while improving housing standards. The authors describe enclosure design, enrichments, and husbandry techniques that facilitate group housing female guinea pigs. No data are included in...
Neonatal (early) handling (EH) and environmental enrichment (EE) of laboratory rodents have been the two most commonly used methods of providing supplementary environmental stimulation in order to study behavioral and neurobiological plasticity. A large body...
Expanding on the National Research Council’s Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of...
The question was raised how the environment of guinea pigs can be best enriched in the research laboratory setting. In summary, social-housing is the most species-appropriate living environment for guinea pigs. If a research protocol...