Advances in bioanalytic methods allow for accurate plasma drug level measurement in small sample volumes. Decreased sample volumes enable serial blood sample collection from one rodent, rather than terminal or sparse sampling from multiple rodents...
An effort to refine rodent blood collection techniques resulted in an examination of alternative methodologies to improve animal welfare and sample quality. Disease model or repeated sample collection resulted in inadequate sample volume, occasional hemolysis...
While numerous published studies have evaluated the effect of housing density on the wellbeing of laboratory mice, little is known on the effect of breeding configuration. The eighth edition of the Guide for the Care...
For infectious disease studies, assessment of feline health is traditionally limited to metrics such as body temperature (BT), change in body weight (BW), and clinical signs (CS). Recently, behavioral ethograms designed for assessment of rabbits...
Sentinel animals are used to monitor the health status of rodents used in research. It is important to screen for potentially pathogenic viruses, parasites, and bacterial organisms to detect and rapidly respond to unwanted pathogens...
Specific positioning for different imaging modalities is essential in our small animal imaging core. While we have different animal holders designed to position the animal inside the MRI, additional securing of the animal to the...
Environmental enrichment is a strategy to improve animal welfare, providing brain plasticity with changes at cellular, molecular and behavioral levels. In order to test the long-term effects of enriched housing and the importance of testosterone...
House mice (Mus musculus) pose a threat to the native flora and fauna on islands, and can cause significant damage wherever they have been introduced. Methods used to eradicate invasive rodents, like house mice, at...
Anaesthesia and analgesia are used frequently in laboratory routine to ensure animal welfare and good scientific outcomes in experiments that may elicit pain or require immobilisation of the animal. However, there is concern regarding the...
The study of laboratory animal behavior has increased steadily over the last decade, with expanding emphasis on a variety of commonly used species. In the United States, this trend was initially focused on species for...