Stress can influence a number of physiological processes including adult neurogenesis, metabolism, cardiovascular function, immune function, neurophysiological function, endocrine function and inflammatory processes following injury. In testing drugs which may be used to treat various...
Some environmental interventions can result in physiologic and behavioral changes in laboratory animals. In this context, the handling of adolescent or adult rodents has been reported to influence exploratory behavior and emotionality. Here we examined...
Philosopher and ethicist Professor Bernard Rollin recently wrote that animal researchers should “do the utmost to minimise animal suffering arising in the course of animal research, and maximise the animal’s ability to live a life...
Ongoing studies and historical data support the finding that deviations or exceptions from the cage density and sanitation frequency standards set forth in the Guide do not negatively affect animal health, welfare, or production parameters...
Bedding influences various parameters in the housing of laboratory mice, such as health, physiology and behaviour (often considered as being integral parts of welfare). Notwithstanding existent studies about bedding preferences of individually tested mice, data...
Despite the reported advantages of corncob bedding, questions have emerged about how comfortable animals find this type of bedding as a resting surface. In this study, encephalography (EEG) was used to compare the effects of...
The authors provide an update to their 2006 report on the successful large-scale captive breeding of the 13-lined ground squirrel (TLGS; Ictidomys tridecemlineatus) in their colony, now a single-source supplier of purpose-bred TLGSs for several...
Environmental enrichment is designed to improve the overall welfare of laboratory animals, including mice. Few studies have directly assessed the effects of different types of enrichment on mouse offspring survival and growth. The authors examined...
Changing soiled cages is an integral part of husbandry, yet it can be a source of stress for both animal and animal care technician. In one case, large geriatric rats weighing around 1 kg did...
The adult male field mouse Mus booduga (n = 42) captured at agricultural field, were housed in non-enriched standard condition (SC) for 7 days and considered as directly from wild (DW). Another two groups of...