Some recommendations in the Guide for the Care and Use of Laboratory Animals (the Guide) are based on best professional judgment. Our current efforts are directed toward replacement with data-driven standards. We demonstrated earlier that...
This article provides details to consider when preparing to use animals in biomedical research. The stress of transport and receipt of animals into a new environment mandate the need for a period of stabilization and...
The aim of the study was to investigate effects of widely recommended nesting material and additional shelters on male mice. The aggressiveness of the mice in their home cages clearly increased in the nest group,as...
Valuable recommendations for the species-adequate housing and species-approriate care of guinea pigs; topics include Housing (enclosure size, substrate, shelter, nesting material), Environmental Enrichment, and Husbandry (light, temperature, humidity, cleaning).
Laboratory dogs are mainly housed indoors and outdoor housing is often considered to be an insecure and uncontrollable alternative. This study aimed to assess the effects of outdoor housing of laboratory dogs on their general...
I conclude from our discussion that commercial prefabricated dwellings for mice are useful only if they are made of GLP-accepted material that the animals can readily gnaw and convert into nesting and bedding material. Since...
In this article, recent publications are examined to determine the potential impact of new scientific evidence on current practices for the housing and care of laboratory rodents. The discussion points out recent advances in technology...
Results of this study suggest that the welfare of kennelled cats is greatly improved if they are provided with the opportunity to perform effective hiding behavior, and that the ability to perform such a behaviour...
In this experiment, 64 pairs of animals of the strain C57BL/6J were used. Half of the animals were born and reared until weaning in standard cages and the other half in cages twice the size...
The report sets out how to provide: optimal enclosure characteristicsand size; social housing; solid flooring and substrate; raised areas; refuges; gnawing objects and dietary enrichment; positive interaction with humans; toys and objects to manipulate; for...