Mantel, N. 1980. Assessing laboratory evidence for neoplastic activity. Biometics 36, 381-399.
Mortality and tumor incidence in corcinogenesis experiments differ between mice caged in the top vs. bottom of the rack.
Includes refinements to diet, bedding or flooring, cage changing, lighting, temperature, noise levels, etc.
Mortality and tumor incidence in corcinogenesis experiments differ between mice caged in the top vs. bottom of the rack.
The preponderance of experimental evidence gathered over the past three decades indicates that exposure to intense noise can lead to a wide variety of functional and structural changes in laboratory animals. Although little information regarding...
Sixty-seven animals from eight primate species were used to assess improved husbandry techniques. The presence of woodchips as a direct-contact litter decreased inactivity and fighting, and increased time spent on the ground. Placing food in...
A woodchip litter substrate reduces abnormal behaviours, primarily self-aggression, and encourages foraging, even in the absence of grain. Comparison between the bare floor and litter with grain showed that in the latter monkeys foraged more...
Improvement of the light fixtures in both rooms doubled the lighting force and increased the breeding rate during the following 12 months approximately 20% in the upper and 130% in the lower cages.
A summary of basic environmental enrichement for group-housed rhesus macaques. The essence of the social primate is lost under the stresses of the nonsocial condition.
Description of an ingenious, simple method to minimize odor, provide species-appropriate nesting opportunities and to facilitate cleaning.
This paper describes the introduction of a modified caging system and the benefits to both the animals and staff. The removal of metal grids at the bottom of the cage, and the introduction of direct...
Amphibians and reptiles differ in many respects from the mammals and birds most commonly used in biomedical research. These differences affect the physical and biological requirements of amphibians and reptiles in captivity. In this contribution...
In this study artificial turf was used as the substrate for a particulate food given to the subjects as an environmental enrichment technique. When their cages were not enriched, eight single-caged subjects exhibited abnormal behaviors...