The key to non-aversive methods of handling lies in understanding what capture method creates the least anxiety in mice: be this tunnel or cupping or another method. It is important that we do not get...
When given the opportunity, mice will choose to build nests using multiple different materials. Studies indicate that providing mice with choices which mimic the natural environment allows laboratory mice to build the best quality nests...
The provision of environmental enrichment to numerous species of laboratory animals is generally considered routine husbandry. However, mouse enrichment has proven to be very complex due to the often contradictory outcomes (animal health and welfare...
Oral administration of substances is a common procedure in scientific experiments using laboratory animals and typically is achieved in conscious animals by using the intragastric gavage technique. While highly effective, this method can be technically...
This simple DIY training treat is great for NHP, swine, rabbits, rodents, and dogs. Note that dehydrated watermelon may resemble muscle tissue!
Laboratory mouse pups are commonly weaned between postnatal day 21–28. Utilization of an exact wean date postpartum is a concrete metric for mouse colony management, but variation can result such as: developmental differences among genetically...
The increasing potential for radiation exposure from nuclear accidents or terrorist activities has intensified the need to develop pharmacologic countermeasures against injury from total body irradiation (TBI). Many initial experiments to develop and test these...
Regardless of the microbiological status of an animal facility, research animals may experience health problems, leading to pain, suffering and distress. Simple and efficient tools are needed to collect data systematically, allowing researchers to react...
Voluntary wheel running is a valuable metabolic intervention and well-established measure of physical activity in preclinical rodent models. Herein, we describe detailed assembly instructions and provide necessary resources for researchers to build their own running...
Murine models of tumor development often require invasive procedures for tumor implantation, potentially causing pain or distress. However, analgesics are often withheld during implantation because of concerns that they may adversely affect tumor development. Previous...