The aim of the study was to investigate effects of widely recommended nesting material and additional shelters on male mice. The aggressiveness of the mice in their home cages clearly increased in the nest group,as...
It was found that heart rate (HR), and to a lesser extent also body temperature (BT), parallels plasma corticosterone (pCORT) values after subjecting the animals to different methods of restraint. Secondly, the acute stress response...
Valuable recommendations for the species-adequate housing and species-approriate care of guinea pigs; topics include Housing (enclosure size, substrate, shelter, nesting material), Environmental Enrichment, and Husbandry (light, temperature, humidity, cleaning).
Our experience-based discussion suggests that social animals benefit from compatible companionship during post-operative recovery. The traditional practice of keeping animals alone in an unfamiliar environment after surgery increases the subjects surgery-associated stress. Providing a familiar...
I conclude from our discussion that commercial prefabricated dwellings for mice are useful only if they are made of GLP-accepted material that the animals can readily gnaw and convert into nesting and bedding material. Since...
In this article, recent publications are examined to determine the potential impact of new scientific evidence on current practices for the housing and care of laboratory rodents. The discussion points out recent advances in technology...
Objective: To investigate the positive effects of four different forms of environmental enrichment on the welfare of mice subjected to restraint stress with the purpose of screening suitable enrichment. Method: Mice undergoing poor welfare due...
A well-known developmental event of retinal maturation is the progressive segregation of retinal ganglion cell (RGC) dendrites into a and b sublaminae of the inner plexiform layer (IPL), a morphological rearrangement crucial for the emergence...
Rats are widely used in biomedical research as animal models for human diseases. However, due to their small body size, blood sampling is complicated and invasive and thereby can seriously interfere with endocrine functions and...
In this experiment, 64 pairs of animals of the strain C57BL/6J were used. Half of the animals were born and reared until weaning in standard cages and the other half in cages twice the size...