Baldwin, A. L., Bell, I. R. 2007. Effect of noise on microvascular integrity in laboratory rats. Journal of the American Association for Laboratory Animal Science [Contemporary Topics in Laboratory Animal Science] 46(1), 58-65.

Housing rats in an environment with high personnel activity increases microvascular leakiness to albumin in the mesenteric microcirculation and causes mast cell degranulation. ...All groups exposed to excess noise had significantly more leaks per venule length and greater leak area per venule length than did the quiet group. However, the number and area of leaks in the rats that received Traumeel or vitamin E were significantly smaller than those in rats exposed to noise only. In addition, mast cell degranulation was signifi- cantly lower in rats given Traumeel. Thus exposure of rats to excessive noise produces structural damage in the mesenteric microvasculature that is significantly reduced by dietary supplements.