Refinement Database

Database on Refinement of Housing, Husbandry, Care, and Use of Animals in Research

This database, created in 2000, is updated every four months with newly published scientific articles, books, and other publications related to improving or safeguarding the welfare of animals used in research.

Tips for using the database:

  • This landing page displays all of the publications in the database.
  • Use the drop-down menus to filter these publications by Animal Type, Setting, and/or Topic.
  • Clicking on a parent category (e.g., Rodent) will include publications relating to all the items in that category (e.g., Chinchilla, Gerbil, Guinea Pig, etc.).
  • You may also add a keyword to further narrow your search.
  • Please note that at this time, only publications dated 2010 or later (with some exceptions) can be filtered by Animal Type and Topic, and only publications dated 2020 or later (with some exceptions) can be filtered by Setting. Most publications older than 2010 can only be searched by keyword. 

Knowledge of the organization and dynamics of the relationships between animals and the environment and its resources is important to meet the needs of any species. We analyzed the effect the presence of a person...

Guidance is almost non-existent as to suitable levels of UV lighting for reptiles and amphibians, or how to achieve satisfactory UV gradients using artificial lighting. The UV-Tool is a working document that seeks to address...

Surveillance of cat shelters by official veterinarians in Austria is based on legal requirements and does not directly assess cat welfare. The aim of this study was to develop animal-based parameters that are feasible to...

Infrared thermal imaging is a non-destructive testing technology that can be used to determine the superficial temperature of objects. This technology has an increasing use in detecting diseases and distress in animal husbandry within the...

The detection and assessment of pain in animals is crucial to improving their welfare in a variety of contexts in which humans are ethically or legally bound to do so. Thus clear standards to judge...

Understanding environmental factors that affect the behavior of cats in cages is important if caretakers are to improve the welfare of confined cats. The aim of this study was to examine the effects of the...

While clinical reptile medicine as a science is in its ascendancy among veterinary surgeons and other interested groups, familiarity with the often related issue of reptilian behavioural and psychological health appears less common. Behavioural change...

Provision of shade to dairy cattle in summer can alleviate negative effects of heat stress. The aim of this study was to investigate the relative importance of shade to lactating dairy cows in different ambient...

This book covers the major issues affecting the welfare of domestic cats. It covers recent developments in our understanding of cat behaviour, considers the ways in which cat welfare is assessed, and addresses the successes...

Evidence indicates that allowing beef calves to stay in the maternal herd beyond the age of natural weaning promotes animal welfare and may enhance the cows' natural reproductive potential.

Commercial caging systems for cats are described and recommendations made for cat-appropriate housing. By housing cats in groups and with appropriate enrichments, according to their physical and psychological needs, researchers can decrease the animal's stress...

Amphibians and reptiles differ in many respects from the mammals and birds most commonly used in biomedical research. These differences affect the physical and biological requirements of amphibians and reptiles in captivity. In this contribution...