Refinement Database

Database on Refinement of Housing, Husbandry, Care, and Use of Animals in Research

This database, created in 2000, is updated every three months with newly published scientific articles, books, and other publications related to improving or safeguarding the welfare of animals used in research.

Links to the full text for publications that appear in open access journals or are published on the AWI website are provided under the abstract.

Tips for using the database:

  • This landing page displays all of the publications in the database.
  • Use the drop-down menus to filter these publications by Animal Type and/or Topic.
  • Clicking on a parent category (e.g., Rodent) will include publications relating to all the items in that category (e.g., Chinchilla, Gerbil, Guinea pig, etc.).
  • You may also add a keyword to further narrow your search.
  • Please note that at this time, only publications dated 2010 or later (with some exceptions) can be filtered by Animal Type and Topic. Most publications older than 2010 can only be searched by keyword. 
The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century. By establishing an animal-centric view on housing and...
This is the 5th volume of selected discussions that took place on the electronic Laboratory Animal Refinement & Enrichment Forum between February 2016 and December 2019. The forum was created in October 2002; it allows...
Humans have shared a long history with horses and today we mainly consider horses as companions for sports and leisure activities. Previously, the human perspective of the human-horse relationship has been investigated but there has...
The aim of this study was to develop and test a tilapia on-farm welfare assessment protocol, based on Brazilian semi-intensive production systems. The study included two mains steps: the elaboration of tilapia welfare protocol and...
Training nonhuman primates (NHPs) to perform cognitive tasks is essential for many neuroscientific investigations, yet laboratory training is a time-consuming process with inherent limitations. Habituating NHPs to the laboratory staff and experimental equipment can take...
Voluntary participation in behavioural studies offers several scientific, management, and welfare benefits to non-human primates (NHPs). Aside from the scientific benefit of increased understanding of NHP cognition, sociality, and behaviour derived from noninvasive behavioural studies...
The impact of behavioural disorders on animal welfare in modern animal husbandry has been much debated. While other abnormal behaviours have been explored at length, there are a paucity of studies on tail-biting in rabbits...
Chimpanzees demand specialized housing and care and the highest degree of attention to animal welfare. The current project used a survey method to collate information on chimpanzee housing and behavioral indices of welfare across all...
Timing of reward is very important when training horses. Incorrect timing can lead to confusion and deleterious behaviors and learning will be impaired. Clicker training can be used as an important tool in training. However...
A prevalent, traditional approach to horse-training is based on the belief that human dominance and leadership over horses is required to gain their respect and compliance. However, this denies the horses’ complex social organisation and...
Body language is important for communication between individuals. Body language is based on the fact that the thought, alone of performing a known action will activate the motor neurons used for the action, resulting in...
Food motivation may influence an animal’s performance in food-rewarded learning tasks. Nevertheless, food is often used as a positive reinforcer in learning tasks to investigate cognitive abilities of farm animals, and to test effects of...
Completely updated and revised, and with a new author team, this second edition of Farm Animal Behaviour continues to provide essential information on normal and stereotypic behaviors in a wide variety of farm animals to...
Understanding the neural circuits underlying equine behaviour has the potential to help optimise strategies of husbandry and training. This review discusses two areas of neurophysiological research in a range of species and relates this information...
The primary purpose of this study was to characterize operant learning performance of young foals. For each of 26 foals, aged 6–20 weeks, learning performance was quantitatively evaluated in a single brief training trial using...
This paper describes a method in which horses learn to communicate by touching different neutral visual symbols, in order to tell the handler whether they want to have a blanket on or not. Horses were...
Positive reinforcement training can be used in many ways to enhance the welfare of captive primates. Training for biologic sample collection is one application of positive reinforcement training. In this study, 35 adult female chimpanzees...
Type 2 diabetes can be a problem for captive chimpanzees. Accurate blood glucose (BG) readings are necessary to monitor and treat this disease. Thus, obtaining voluntary samples from primates through positive reinforcement training (PRT) is...
This is the third volume of discussions that took place on the Laboratory Animal Refinement & Enrichment Forum (LAREF). This forum is dedicated to the exchange of personal experiences of refining the conditions under which...
Positive reinforcement training (PRT) is used at various biomedical research facilities and zoos in order to facilitate animal husbandry activities as well as veterinary procedures. Previous research suggests that the use of PRT helps alleviate...
Positive reinforcement training (PRT) methods can be applied to gain the voluntary cooperation of laboratory primates with the collection of biological samples. Information will be provided on training techniques used and the amount of training...
In the last decade several surveys of primate care and training programs highlight a common theme; despite scientific evidence that animal training can be effective in reducing stress, increasing efficiency and improving veterinary care, animal...
This review will examine how individual differences in temperament might affect, or be affected by, behavioral management practices for captive primates. Measuring temperament may help us predict the outcome of social introductions. It can also...
Training captive nonhuman primates to voluntarily participate in a variety of necessary research and medical procedures is a valuable refinement in the management of captive primates. For the purposes of this talk, training programs require...
At the Oregon National Primate Research Center, we train animals to enter transfer boxes using positive reinforcement training (PRT), a type of training in which the trainer reinforces desired behaviors (such asentering the transfer box)...

Share This!