Refinement Database

Database on Refinement of Housing, Husbandry, Care, and Use of Animals in Research

This database, created in 2000, is updated every three months with newly published scientific articles, books, and other publications related to improving or safeguarding the welfare of animals used in research.

Links to the full text for publications that appear in open access journals or are published on the AWI website are provided under the abstract.

Tips for using the database:

  • This landing page displays all of the publications in the database.
  • Use the drop-down menus to filter these publications by Animal Type and/or Topic.
  • Clicking on a parent category (e.g., Rodent) will include publications relating to all the items in that category (e.g., Chinchilla, Gerbil, Guinea pig, etc.).
  • You may also add a keyword to further narrow your search.
  • Please note that at this time, only publications dated 2010 or later (with some exceptions) can be filtered by Animal Type and Topic. Most publications older than 2010 can only be searched by keyword. 

Rabbits are the third species in terms of number of animals reared for meat production in the world. However, in comparison to other species, very few studies have focused on their welfare. The aim of...

Temperament can be defined as interindividual differences in behavior that are stable over time and in different contexts. The terms ‘personality’, ‘coping styles’, and ‘behavioral syndromes’ have also been used to describe these interindividual differences...

This is the 5th volume of selected discussions that took place on the electronic Laboratory Animal Refinement & Enrichment Forum between February 2016 and December 2019. The forum was created in October 2002; it allows...

Nociceptive threshold (NT) testing is widely used for the study of pain and its alleviation. The end point is a normal behavioural response, which may be affected by restraint or unfamiliar surroundings, leading to erroneous...

We argue that there is currently an under-reporting of the ways in which pain can be associated with problem behavior, which is seriously limiting the recognition of this welfare problem. A review of the caseloads...

As pets are considered members of the family, their health has received widespread attention. Since pets cannot talk and complain when they feel uncomfortable, monitoring vital signs becomes very helpful in disease detection, as well...

At any moment, there are millions of cats housed in foster care facilities for abandoned and stray animals for various reasons worldwide. Care, management and regulation among these facilities differ. Moreover, shelters can never substitute...

The behavioural assessment of individual animals in stressful situations should consider measures which are consistent across repeated testing, and therefore truly representative of an individual's behaviour. Here we report a study conducted on 40 neutered...

Our objective was to identify and characterize the types of vocalization other than meowing (VOM) in two contexts, a pleasant and an aversive situation, and to study the effect of the sex of the animal...

This second edition is fully revised, expanded, and comprehensively updated with the most current knowledge about the full array of mental health issues seen in animals. Written by key opinion leaders, internationally-recognized experts and specialists...

Not all animals behave identically when faced with the same situation. These individual differences in the expression of their behavior could be due to many factors, including medical conditions. These medical problems can change behavior...

This article describes the rehoming of 10 laboratory female rabbits now living as a group in a private shelter.

Completely updated and revised, and with a new author team, this second edition of Farm Animal Behaviour continues to provide essential information on normal and stereotypic behaviors in a wide variety of farm animals to...

The contemporary approach to pain measurement in people and animals seeks to measure the affective (emotional) component of the pain experience using structured questionnaires with formal scoring methodology. Chronic pain has wide-ranging impacts which affects...

The aim of this study was to assess hair cortisol concentrations in New Zealand white rabbits (Oryctolagus cuniculus) that were subjected to relocation and surgery to evaluate HPA-axis activity; in addition, we used this marker...

To treat pain, we must look for it, recognise it and in some way measure it; this requires validated tools that work in a busy clinical environment. In addition to preventing suffering, effective treatment of...

Previously the authors described the derivation of an intervention level for the Glasgow Composite Measure Pain Scale (CMPS) short form tool for assessing acute pain in dogs. More recently, the authors reported the validation of...

The RSPCA/UFAW Rodent (and now Rabbit) Welfare Group held a one-day meeting on 1 November 2016 at the University of Edinburgh and was attended by 70 delegates. Presentation topics included refinements in blood sampling rodents...

To investigate how long relocation modified hair cortisol concentrations in New Zealand white rabbits, 19 rabbits were subjected to a change in their breeding facility at the beginning of the trial and then were kept...

Understanding individual responses to stress is a key aspect of maintaining optimal animal welfare. This is especially important where animals are being kept in sub-optimal environments or where the species may not clearly demonstrate stress...

Leyhausen’s (1979) work on cat behaviour and facial expressions associated with offensive and defensive behaviour is widely embraced as the standard for interpretation of agonistic behaviour in this species. However, it is a largely anecdotal...

Although the recognition of pain, distress and discomfort has already been described in 1985 by Morton and Griffiths there is still very little known about the establishment of score sheets especially, regarding postsurgical pain and...

The goal of the present study was to assess how cats react to tastes previously reported to be preferred or avoided relative to water. To this end, the facial and behavioral reactions of 13 cats...

The RSPCA/UFAW Rodent Welfare Group has held a one-day meeting every autumn for the last 21 years, so that its members can discuss current welfare research, exchange views on rodent welfare issues and share experiences...

For infectious disease studies, assessment of feline health is traditionally limited to metrics such as body temperature (BT), change in body weight (BW), and clinical signs (CS). Recently, behavioral ethograms designed for assessment of rabbits...

Share This!