Refinement Database

Database on Refinement of Housing, Husbandry, Care, and Use of Animals in Research

This database, created in 2000, is updated every three months with newly published scientific articles, books, and other publications related to improving or safeguarding the welfare of animals used in research.

Links to the full text for publications that appear in open access journals or are published on the AWI website are provided under the abstract.

Tips for using the database:

  • This landing page displays all of the publications in the database.
  • Use the drop-down menus to filter these publications by Animal Type and/or Topic.
  • Clicking on a parent category (e.g., Rodent) will include publications relating to all the items in that category (e.g., Chinchilla, Gerbil, Guinea pig, etc.).
  • You may also add a keyword to further narrow your search.
  • Please note that at this time, only publications dated 2010 or later (with some exceptions) can be filtered by Animal Type and Topic. Most publications older than 2010 can only be searched by keyword. 

The aim of this study was to verify the motivation of rabbit does to social contact or seclusion. The results of two different research activities assessed in Italy (experiment 1) and Germany (experiment 2) through...

The quality of the social environment should be studied as one of the welfare components of dairy herds. Licking and preference between cows are important socio-positive experiences in this context.The aims of this study were...

In the wild, rabbits (Oryctolagus cuniculus) are social but territorial. Recent surveys suggest that over half of pet rabbits are housed singly. We aimed to compare welfare in single versus paired rabbits. We predicted singletons...

Calves reared on pasture learn to graze from their dam and conspecifics during weaning. Social learning can be beneficial for calf performance and welfare, and pair-housing and companionship on pasture have been proposed as management...

The aim of this study was to evaluate the effects of pair versus individual housing on performance, health, and behavior of dairy calves. Thirty female Holstein dairy calves were assigned to individual (n = 10)...

This is the 5th volume of selected discussions that took place on the electronic Laboratory Animal Refinement & Enrichment Forum between February 2016 and December 2019. The forum was created in October 2002; it allows...

Although group housing of naturally social animals like rabbits (Oryctolagus cuniculus) is desirable for ethical reasons, social conflicts can significantly increase the risk for injuries as well as stress incidences and negatively affect their welfare...

The study aimed at evaluating different management protocols of grouping does in regard to aggressive interactions and the establishment of a hierarchy under commercial conditions. Fifty-seven multiparous rabbit does of the Hycole hybrid maternal line...

Elizabethan collars (E-collars) are commonly used in various species to safeguard healing wounds. However, E-collars inadvertently restrict the expression of normal species-typical behaviors, including coprophagy, self-grooming, and social housing. To maintain social housing in accordance...

Dairy calves are often housed in individual pens, which limits play behaviour. This study investigates whether the motivation for social play builds up during periods of deprivation hereof. Sixteen mixed-sex pairs of calves (33 ±...

Aggressiveness is one of the main problems in group housing of rabbit does. The aim of the experiment was to investigate the frequency of aggressiveness and mating behaviour as well as the lifespan of does...

This study assessed the effects of an elevated plastic-slatted platform and/or a plastic hiding tube in collective pens with large group sizes (27 or 36 rabbits/pen; 16 rabbits/m2) on the performance and welfare of rabbits...

We evaluated the effects of two types of colony cages, in which rabbit does were always in a group (C1), and where they were in combi cages furnished with removable internal walls to allow both...

Individual housing of dairy calves is common farm practice, but has negative effects on calf welfare. A compromise between practice and welfare may be housing calves in pairs. We compared learning performances and affective states...

This article describes the rehoming of 10 laboratory female rabbits now living as a group in a private shelter.

Dairy calf welfare concerns are growing and new evidence suggests that the early life environment influences appropriate physical, behavioral, and cognitive development lasting into adulthood. This review highlights key evidence for the impacts of housing...

This work aimed at evaluating the effects of housing system, pen floor type, and lactation management on rabbit doe and kit performance throughout a reproductive cycle, including categorization of aggressiveness and injuries. Forty multiparous pregnant...

Though European rabbits are a social species, socially housing them can be challenging. Therefore, there must be a thorough understanding of behaviors and social structures of pair-housed laboratory rabbits. Here we present a protocol to...

Rabbits are usually singly housed in laboratories, but a new emphasis on providing social housing for social species has prompted exploration of alternative housing for this species. However, a paucity of literature on the social...

The aim of this work was to study how the group size and the number of doorways in a pen may influence the aggressive interactions throughout the reproductive cycle among does kept in a part-time...

The 8th Edition of the Guide for the Care and Use of Laboratory Animals clarified its language regarding housing social species, specifying that, “Single housing of social species should be the exception…”. This is a...

Group housing is becoming the standard for many farm animal species, as it is seen as a more welfare friendly way of keeping gregarious animals. Aggression between female breeding rabbits currently obstructs the implementation of...

Contentious issues in calf rearing include milk feeding level and single versus group housing. The current study was performed on a high-producing 170 Holstein cow dairy farm to investigate the impact of nutrition and housing...

This poster is based on welfare improvements gained from group housing rabbits in floor pens in the new Antibody Production Facility with a focus on development, behaviours and environmental enrichment in both male and female...

The objective of the study was to investigate if environmental enrichment and the composition of the social group would affect the behavior and relative brain weight of growing rabbits. Rabbits (72 males and 72 females)...

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