Refinement Database

Database on Refinement of Housing, Husbandry, Care, and Use of Animals in Research

This database, created in 2000, is updated every three months with newly published scientific articles, books, and other publications related to improving or safeguarding the welfare of animals used in research.

Links to the full text for publications that appear in open access journals or are published on the AWI website are provided under the abstract.

Tips for using the database:

  • This landing page displays all of the publications in the database.
  • Use the drop-down menus to filter these publications by Animal Type and/or Topic.
  • Clicking on a parent category (e.g., Rodent) will include publications relating to all the items in that category (e.g., Chinchilla, Gerbil, Guinea pig, etc.).
  • You may also add a keyword to further narrow your search.
  • Please note that at this time, only publications dated 2010 or later (with some exceptions) can be filtered by Animal Type and Topic. Most publications older than 2010 can only be searched by keyword. 
In this study, a pig toilet was installed on an organic pig farm, which enabled pigs to use a lying area littered with straw and keep it clean. The pig toilet was separated into a...
Little is known on the effect of light on pig behaviour. The choice behaviour of weaned piglets kept under two different light-emitting diode (LED) illuminance levels was investigated: 32 piglets (in two batches) were housed...
Sows in an extensive setting maintain small, stable matrilineal social groups comprised of familiar, and often genetically related, conspecifics. Providing conditions in an intensive farm setting which allow similar social groups could reduce aggression by...
Improving the housing of pregnant sows by giving them more space and access to deep straw had positive effects on their welfare, influenced their maternal behavior and improved the survival of their offspring. The present...
Across a period of 54 months, several changes were made to the feeding protocols of 32 adult chimpanzees living at the Yerkes National Primate Research Center Field Station. Before implementing any changes in diet, baseline...
In Canada, the 2014 Code of Practice for the Care and Handling of Pigs proposed the continued operation of existing stall barns after 2024 on condition that bred sows be given access to periodic exercise...
This study aimed at evaluating the effects of unpredictability on behavioral and clinical aspects of Geoffroy's woolly monkey (Lagothrix cana cana) - a frugivorous Amazonian primate species - under human care. We studied seven individuals...
Today's livestock agriculture faces major changes in domestic pig husbandry—besides animal health and productivity, aspects of animal welfare and animal-friendly husbandry systems for pigs increasingly gain attention. To get a basic and current overview of...
Occupational enrichment emerges as a promising strategy for improving the welfare of farmed animals. This form of enrichment aims to stimulate cognitive abilities of animals by providing them with more opportunities to interact with and...
Unfulfilled exploratory behavior in pigs has been linked to tail biting, which causes reduced performance and welfare. Provision of straw can reduce tail biting, but large straw rations can cause poor hygiene in pens. This...
In conclusion, the investigations carried out up to now demonstrate that during the early stages fish show high sensitivity to many types of stressors involving an array of responses to overcome alterations that could affect...
In commercial pig production, stressful events are common and can have detrimental impacts on the pig's health and welfare, as well as on the performance of the farm. Supplementary magnesium may reduce stress, and subsequent...
Piglets weaned under commercial systems are greatly stressed by maternal separation, abrupt changes in the diet and mixing of litters. Intensive agonistic interactions exacerbate this challenge for piglets. We investigated effects of older conspecific presence...
The importance of social stability and its influence on the expression of the social behaviour repertoire in domestic animals remains poorly understood, especially for affiliative behaviours and other putative socio-positive behaviours such as social play...
This 30-chapter volume informs students and professionals about the behavioral biology of animals commonly housed in laboratory and other captive settings. Each species evolved under specific environmental conditions, resulting in unique behavioral patterns, many of...
The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century. By establishing an animal-centric view on housing and...
The aim of this study was to investigate herd cortisol levels as an indicator of stress during gestation in three different feeding systems. Twelve commercial Danish herds with 800 to 3050 sows were included, with...
This study examines effects of opening hinged farrowing crates 4 or 7 days post-farrowing. Sows (n = 696) allocated to 3 treatments: PC—crate closed, T4—crate opened day 4, and T7—crate opened day 7 were assessed...
Housing pigs within their thermal comfort zone positively impacts productivity and performance. However, fundamental information on behavioral thermoregulatory responses of individual and group-housed pigs is meager. As a gregarious species, pigs prefer to be near...
Farrowing stalls are used in the United States swine industry to reduce pre-weaning piglet mortality, enable efficient individual animal management, and decrease facility construction and operating costs. The quantity and quality of space provided for...
Despite being phased out in the EU, several states in the USA and other select countries such as Australia, gestation stalls remains a common sow housing system worldwide. In Canada, the 2014 Code of Practice...
Appropriate end-points are integral to the refinement of laboratory animal experiments. Our recent experience has highlighted that ambiguity around end-points is hampering their adoption in experiments that cause severe suffering to fish. In toxicology, the...
Animal welfare scientists have accumulated knowledge and developed interventions to improve livestock welfare, but these are poorly adopted in commercial practice. Animal welfare interventions are rarely tested for economic viability and this limits their uptake...
There are a multitude of health monitoring techniques/ methods available. It can be difficult to know which of these to use and when to use them. This is an attempt to simplify, maximise the efficacy...

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