Refinement Database

Database on Refinement of Housing, Husbandry, Care, and Use of Animals in Research

This database, created in 2000, is updated every three months with newly published scientific articles, books, and other publications related to improving or safeguarding the welfare of animals used in research.

Links to the full text for publications that appear in open access journals or are published on the AWI website are provided under the abstract.

Tips for using the database:

  • This landing page displays all of the publications in the database.
  • Use the drop-down menus to filter these publications by Animal Type and/or Topic.
  • Clicking on a parent category (e.g., Rodent) will include publications relating to all the items in that category (e.g., Chinchilla, Gerbil, Guinea pig, etc.).
  • You may also add a keyword to further narrow your search.
  • Please note that at this time, only publications dated 2010 or later (with some exceptions) can be filtered by Animal Type and Topic. Most publications older than 2010 can only be searched by keyword. 
In order to base welfare assessment of dairy cattle on real-time measurement, integration of valid and reliable precision livestock farming (PLF) technologies is needed. The aim of this study was to provide a systematic overview...
Evaluation of animal behavior provides information on health and well-being in animals. In this preliminary study, we investigated the effectiveness of an accelerometry approach to evaluate changes in health status of cattle by combining physical...
When we treat an animal’s welfare as an individual experience, we should consider the possibility that it may be associated with individual differences in personality. We tested for such associations in 44 socially housed rhesus...
The National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) is working with industry to promote social housing during cardiovascular telemetry recordings within non-rodent safety pharmacology and toxicology studies. Following surveys...
Background: Neuroscience studies with macaque monkeys may require cranial implants to stabilize the head or gain access to the brain for scientific purposes. Wound management that promotes healing after the cranial implant surgery in non-human...
In a 2018 AALAS webinar on Sheep and Goat Analgesia, Dr. Susie Vogel, a small ruminant expert, introduced the concept of getting sheep and goats to willingly take medication by putting it in a tasty...
Previous reports suggest that female macaques with greater similarity in emotionality and nervous temperament, as evaluated in a well-established BioBehavioral Assessment (BBA) at the California National Primate Research Center, were more likely to form successful...
The review aimed to collect information about the wearable wireless sensor system (WWSS) for cattle and to conduct a systematic literature review on the accuracy of predicting the physiological parameters of these systems. The WWSS...
Personality is often defined as the behaviour of individual animals that is consistent across contexts and over time. Personality traits may become unstable during stages of ontogeny from infancy to adulthood, especially during major periods...
This is the 5th volume of selected discussions that took place on the electronic Laboratory Animal Refinement & Enrichment Forum between February 2016 and December 2019. The forum was created in October 2002; it allows...
Husbandry procedures may cause behavioral and physiological changes to animals living in captivity. However, an individual’s reaction is not uniform and may be related to different coping strategies. In this study, we analyzed whether and...
Examining the literature suggests equine personality is of interest to behavior and welfare scientists and those involved in the equine industry. Study and assessment of personality is critical because of the profound implications certain traits...
This systematic review explores the use of on-animal sensors in sheep and their potential application in objective welfare monitoring. The key questions posed were: To what extent can current scientific knowledge inform a sensor-based approach...
The assessment of personality in farm animals and its relation to other behavioural and physiological traits is of growing scientific and practical interest. Therefore, the aims of the present study were first to assess the...
The RSPCA/UFAW Rodent (and now Rabbit) Working Group has held a one-day meeting every autumn for the last 25 years, so that its members can discuss current welfare research, exchange views on welfare issues and...
Cattle mother-offspring contact calls encode individual-identity information; however, it is unknown whether cattle are able to maintain individuality when vocalising to familiar conspecifics over other positively and negatively valenced farming contexts. Accordingly, we recorded 333...
Personality, defined as consistent between-individual variation in clusters of behavioral traits independent of factors such as age or sex, emerges in most animal species tested so far. The number of invertebrate species discovered to have...
Automated monitoring of behaviour can offer a wealth of information in circumstances where observing behaviour is difficult or time consuming. However, this often requires attaching monitoring devices to the animal which can alter behaviour, potentially...
Mounted police horses and riders are repeatedly subjected to demanding and stressful situations. Intensive selection and training of police horses is required to ensure performance, safety and welfare of the horses and their riders. At...
Horse handlers often encounter problem behaviour resulting from a lack of stimulus control. Handlers are often only 15% of the weight of horses, which evolved strong flight responses. Therefore, many riders and handlers resort to...
Previous research has repeatedly shown both personality and psychological stress to predict gastrointestinal disorders and chronic diarrhea in humans. The goal of the present research was to evaluate the role of personality, as well as...
Social instability in primate groups has been used as a model to understand how social stress affects human populations. While it is well established that individual cercopithecines have different temperaments or personalities, little is known...
Individual variation in behaviour has been shown to have important ecological and evolutionary consequences. Research on animal personality has therefore received considerable attention, yet some methodological issues remain unresolved. We tested whether assessing personality by...
Continuous tethered infusions in any animal model pose a unique set of problems. These problems are amplified when nonhuman primates are the model. A high tolerance to the tether system by an animal model is...
Recent research suggests that personality, defined as consistent individual behavioral variation, in farm animals could be an important factor when considering their health, welfare, and productivity. However, behavioral tests are often performed individually and they...

Share This!